1. ERGO Genome Analysis and Discovery System
ERGO provides a systems-biology informatics toolkit centered on comparative genomics to capture, query and visualize sequenced genomes. Building upon the most comprehensive genomic database available anywhere integrated with the largest collection of microbial metabolic and non-metaboli...
标签:Metabolic reconstruction,Phylogenetics, Comparative genomics, SNP Annotation, SNP discovery, Alignment, Exome analysis, Metagenomics,Pathway analysis, Comparative transcriptomics, Functional Genomics, Gene Expression Analysis, Genome Wide Association Stud
2. Tablet
Tablet is a lightweight, high-performance graphical viewer for next generation sequence assemblies and alignments. Tablet is a lightweight, high-performance graphical viewer for next generation sequence assemblies and alignments. Tablet is a lightweight, high-performance graphical...
标签:Genomics, Genotyping,Comparative genomics
3. MetaSim
The software can be used to generate collections of synthetic reads. Générateur de reads ou de mate-pairs à partir d’un modèle d’erreur de séquençage adaptable (Sanger, 454 ou Illumina) et d’une base de données. Générateur de reads ou de mate-pairs à partir d’un modèle d’erreur de...
标签:Metagenomics, Genomics
4. LAST
Short read alignment program incorporating quality scores
标签:Genomics, Comparative genomics
5. CloudBurst
CloudBurst is a parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes.
标签:SNP discovery, Genotyping,Personal genomics
6. SeqAn
C++ template library with many sequence analysis algorithms and datastructures.
标签:Sequence analysis, Genomics,Phylogenetics
7. Prinseq
PRINSEQ is a sequence processing tool that can be used to filter, reformat and trim genomic and metagenomic sequence data. It generates summary statistics of the input in graphical and tabular formats that can be used for quality control steps. PRINSEQ is available as both standalone an...
标签:Metagenomics, Genomics,Metatranscriptomics
8. Bismark
Bismark is a tool to map bisulfite treated sequencing reads and perform methylation calling in a quick and easy-to-use fashion.
标签:Epigenomics, Genomics, DNA methylation
9. RSAT peak-motifs
A workflow combining a series of time- and memory-efficient motif analysis tools to extract motifs from full-size collections of peaks as generated by ChIP-seq, ChIP-chip or other ChIP-X technologies.
标签:ChIP-Seq, Regulatory genomics,Epigenomics
10. Omixon Variant Toolkit
Omixon Target Standard, Target HLA and Target Pro are designed to help clinical, diagnostic and research labs to efficiently get the maximum accuracy and precision from their targeted NGS data.
标签:Comparative genomics, Mapping,Sequence analysis, Read alignment, InDel discovery,SNP discovery
11. CopySeq
CopySeq analyzes the depth-of-coverage of whole genome resequencing data to predict CNVs and to infer quantitative locus copy-number genotypes.
标签:Structural variation, Copy number estimation, Genotyping,Personal genomics
12. DIAL
A computational pipeline for identifying single-base substitutions between two closely related genomes without the help of a reference genome.
标签:SNP discovery, Comparative genomics
13. Lasergene
Lasergene is a comprehensive DNA and protein sequence analysis software suite comprised of seven applications which include functions ranging from sequence assembly and SNP detection, to automated virtual cloning and primer design.
标签:Alignment, De novo sequencing,De-novo assembly, Genomics,InDel discovery, Integrated solution, Mapping,Phylogenetics, Protein structure analysis, Read alignment, SNP discovery,Sequence analysis,Transcription Factor Binding Site identification
14. DeconSeq
DeconSeq can be used to automatically detect and efficiently remove any type of sequence contamination from metagenomic datasets, including human or other host sequences. The tool uses a modified version of the BWA-SW aligner and can be applied to longer-read datasets (150+bp read lengt...
标签:Metagenomics,Metatranscriptomics, Genomics
15. GPS
GPS is a high spatial resolution peak detection algorithm for ChIP-Seq data.
标签:Genomics, ChIP-Seq,Transcription Factor Binding Site identification,Regulatory genomics epigenomics
16. ConDeTri
ConDeTri is a content dependent read trimming software for Illumina/Solexa sequencing data
标签:RNA-Seq, DNA-Seq, Genomics
17. Sim4cc
Cross-species spliced alignment of ESTs to genomes
标签:RNA-Seq Alignment, Comparative genomics
18. BRCA-diagnostic
Computational screening test for BRCA1/2 mutants in human genomic DNA
标签:Personal genomics
19. GenomeView
GenomeView is a next-generation stand-alone genome browser and editor initiated in the BSB group at VIB and currently developed at Broad Institute. It provides interactive visualization of sequences, annotation, multiple alignments, syntenic mappings, short read alignments and more. Man...
标签:Genomics, Comparative genomics, Comparative transcriptomics,Transcriptomics, Gene annotation retrieval, Quality Control, Sequencing, Sequence analysis
20. CNANorm
A normalization method for Copy Number Aberration in cancer samples.
标签:Cancer biology, Copy number estimation, Genomics